Preliminary study of the effect of type 2 diabetes mellitus on bone metabolism in the elderly

Objective To investigate the influence of type 2 diabetes mellitus(T2DM) in bone metabolism in the elderly,and to analyze the relevant factors.Methods Bone mineral density(BMD) was measured in 194 elderly patients using dual-energy X-ray absorptiometry.BMD lower than 2.0 standard deviation of the peak BMD was the diagnostic level of OP.The OP detection rates in T2DM group,non-T2DM(control group),and in patients with over 6-year T2DM(T2DM6) were compared and analyzed.Results(1) The incidence of OP in T2DM group was higher than that in control group(P 0.05).The incidence of OP in T2DM6 group was higher than that in control group(P 0.05).(2) BMD decreased with the growing of age and extension of the T2DM course.Female T2DM patients were seven times more than male patients.BMI was a protective factor.Conclusion There was greater impact on BMD for the elderly T2DM patients with longer disease course.High body weight was protective factor for BMD in T2DM patients.Bone mass loss occurred in elderly T2DM patients a few years ago.We must pay more attention on prevention and treatment of OP.