2014•Infectious Disease InformationRequires access

Recent advances in resistance mechanisms of Acinetobacter baumannii and treatment strategies

Yonggang Zhou

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Abstract

Acinetobacter baumannii has the potent abilities of acquiring drug resistance and clonal propagation, and the mechanisms of resistance to multiple antibiotics are very complex. Multidrug-resistant and pandrug-resistant Acinetobacter baumannii are prevalent worldwide and in China Acinetobacter baumannii has become one of the most important pathogens that cause nosocomial infections, which has posed new challenges for the treatment of nosocomial infections. So it is of great importance to recognize the resistance mechanisms and formulate effective treatment strategies. This article gives an overview of the recent advances in the resistance mechanisms of Acinetobacter baumannii and treatment strategies to combat Acinetobacter baumannii infections.

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What this paper is about

Acinetobacter baumannii has the potent abilities of acquiring drug resistance and clonal propagation, and the mechanisms of resistance to multiple antibiotics are very complex. Multidrug-resistant and pandrug-resistant Acinetobacter baumannii are prevalent worldwide and in China Acinetobacter baumannii has become one of the most important pathogens that cause nosocomial infections, which has posed new challenges for the treatment of nosocomial infections. So it is of great importance to recognize the resistance mechanisms and formulate effective treatment strategies. This article gives an overview of the recent advances in the resistance mechanisms of Acinetobacter baumannii and treatment strategies to combat Acinetobacter baumannii infections.

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Available abstract

Acinetobacter baumannii has the potent abilities of acquiring drug resistance and clonal propagation, and the mechanisms of resistance to multiple antibiotics are very complex. Multidrug-resistant and pandrug-resistant Acinetobacter baumannii are prevalent worldwide and in China Acinetobacter baumannii has become one of the most important pathogens that cause nosocomial infections, which has posed new challenges for the treatment of nosocomial infections. So it is of great importance to recognize the resistance mechanisms and formulate effective treatment strategies. This article gives an overview of the recent advances in the resistance mechanisms of Acinetobacter baumannii and treatment strategies to combat Acinetobacter baumannii infections.

Key concepts: Acinetobacter baumannii, Acinetobacter, Drug resistance, Antibiotic resistance, Intensive care medicine, Multiple drug resistance, Antibiotics, Microbiology

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