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Expression and significance of ER、PR and Her-2 in breast cancer tissue

Dehong Zou

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Abstract

Objective To observe the expression and significance of estrogen receptor(ER)、prosgestogen receptor(PR)and Her-2 in breast cancer.Methods The expressions of ER、PR and Her-2 were detected by immunohistochemical staining in 1 049 cases of breast cancer proved pathologically.Results The positive rates of ER、PR and Her-2 protein were 58.63%、51.10% and 21.54% respectively in 1 049 cases with breast cancer.Significant dependablity were found in the expression of ER、PR and Her-2(P0.05).Conclusions The expressions of ER,PR,Her-2 in breast cancer tissue are positive.All of them participate the genesis and development of breast cancer.

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What this paper is about

Objective To observe the expression and significance of estrogen receptor(ER)、prosgestogen receptor(PR)and Her-2 in breast cancer.Methods The expressions of ER、PR and Her-2 were detected by immunohistochemical staining in 1 049 cases of breast cancer proved pathologically.Results The positive rates of ER、PR and Her-2 protein were 58.63%、51.10% and 21.54% respectively in 1 049 cases with breast cancer.Significant dependablity were found in the expression of ER、PR and Her-2(P0.05).Conclusions The expressions of ER,PR,Her-2 in breast cancer tissue are positive.All of them participate the genesis and development of breast cancer.

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Available abstract

Objective To observe the expression and significance of estrogen receptor(ER)、prosgestogen receptor(PR)and Her-2 in breast cancer.Methods The expressions of ER、PR and Her-2 were detected by immunohistochemical staining in 1 049 cases of breast cancer proved pathologically.Results The positive rates of ER、PR and Her-2 protein were 58.63%、51.10% and 21.54% respectively in 1 049 cases with breast cancer.Significant dependablity were found in the expression of ER、PR and Her-2(P0.05).Conclusions The expressions of ER,PR,Her-2 in breast cancer tissue are positive.All of them participate the genesis and development of breast cancer.

Key concepts: Breast cancer, Immunohistochemistry, Estrogen receptor, Medicine, Cancer, Progesterone receptor, Internal medicine, Oncology

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