Observation on Clinical Efficacy of Trimetazidine for the Adjuvant Treatment of Coronary Heart Disease

Objective To investigate the clinical efficacy and safety of trimetazidine for the adjuvant treatment of coronary heart disease.Methods 60 patients with coronary heart disease in our hospital from April 2010 to September 2013 were randomly divided into control group and observation group,with 30 cases in each group.Patients in the control group were treated with atorvastatin,while patients in the observation group were treated with atorvastatin combined with trimetazidine.The exercise duration time,induced angina onset time,1 mm ST segment depression time before and after treatment,the total effective rate and incidence of adverse reactions of two groups were compared.Results The exercise duration time,induced angina onset time and 1 mm ST segment depression time after treatment of observation group were significantly longer than those of control group(all P0.05).The total effective rate of observation group was93.3%,significantly higher than 70.0% of control group(P0.05).No serious adverse reaction was found in both groups(P0.05).Conclusions Trimetazidine for the adjuvant treatment of coronary heart disease has exact effect.It can effectively improve the cardiac function with few adverse reactions.