Altered Expression of C-erbB2 and P16 Gent in Gastric Carcinoma

Objective To probe into the value of C-erbB_2 and P16 agent determining the diagnosis of carcinoma of stomach.Methods By means of immune grouped comparison,analysis has been carried out on C-erbB_2 and P16 manifestation products of carcinoma of stomach,non-typical gastric hyperplasia,gastric ulcer and normal gastric tissue slices.Results The positive incidence of C-erbB_2 of carcinoma of stomach,stomach and severe non-typical hyperplasia is obviously higher than that of the control group and gastric ulcer group.The P16 agent manifestation of carcinoma of stomach,stomach and severe non-typical hyperplasia is obviously lower than that of the control group and gastric ulcer group.Conclusion High C-erbB_2 agent manifestation and low P16 agent manifestation are both the base of molecular biochemistry and it attains great significance in testing the manifestation level of these two agents in clinical diagnosis.