Relationship between Sex Hormones and Serum Lipid Levels in Postmenopausal Women with Cerebral Infarction

Objective To study the changes of sex hormone and serum lipid levels in postmenopausal women with cerebral infarction. Method 25 postmenopausal women with cerebral infarction (group A); 23 healthy postmenopausal women (group B) and 20 healthy prmenopausal women (group C) were selected to compare the serum levels of estradiol (E 2), progesterone (P), follicle stimulating hormone (FSH), luteinizing hormone (LH), testosterone (T), total cholesterol (TC), triglyceride (TG), high density lipoprotein-cholesterol (HDL-C) and low density lipoprotein-cholesterol (LDL-C). Result Analysis of variance revealed that serum levels of T, FSH, LH, TC, TG, LDL-C were significantly higer while E 2 and HDL-C lower in group A than those in group B and group C. Correlation analysis showed that serum E 2 level was negatively correlated with serum FSH, LH, TC, TG and LDL-C levels, but positively correlated with HDL-C. Conclusion The study indicates that sex hormones disorder and adverse serum lipid profile are important risk factors of cerebral infarction in postmenopausal women.