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Detection and Clinical Significance of Coagulation Indicators in Patients with Pregnancy-induced Hypertension

LI Hao-xu

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Abstract

Objective To explore the cystatin C and coagulation index changes of mild pregnancy-induced hypertension(referred to as PIH)patients,and discuss its clinical significance.Methods Serum cystatin C content and coagulation index(PT and APTT,TT,and FIB)of 71 hospitalized patients with mild PIH and 90 healthy maternal cases were tested and compared.Results PIH cystatin C concentration(1.61 ± 0.28)mg/Lwas significantly higher than the control group(1.23±0.32)mg/L(P0.05),while creatinine did not change significantly.PT,TT were significantly reduced(P0.05),the FIB content and the percentage of AT-III were significantly increased(P0.05)and there was no significant difference in APTT.Conclusion Patients with mild PIH have a hypercoagulable tendency and decreased renal function,which calls for due attention.

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What this paper is about

Objective To explore the cystatin C and coagulation index changes of mild pregnancy-induced hypertension(referred to as PIH)patients,and discuss its clinical significance.Methods Serum cystatin C content and coagulation index(PT and APTT,TT,and FIB)of 71 hospitalized patients with mild PIH and 90 healthy maternal cases were tested and compared.Results PIH cystatin C concentration(1.61 ± 0.28)mg/Lwas significantly higher than the control group(1.23±0.32)mg/L(P0.05),while creatinine did not change significantly.PT,TT were significantly reduced(P0.05),the FIB content and the percentage of AT-III were significantly increased(P0.05)and there was no significant difference in APTT.Conclusion Patients with mild PIH have a hypercoagulable tendency and decreased renal function,which calls for due attention.

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Available abstract

Objective To explore the cystatin C and coagulation index changes of mild pregnancy-induced hypertension(referred to as PIH)patients,and discuss its clinical significance.Methods Serum cystatin C content and coagulation index(PT and APTT,TT,and FIB)of 71 hospitalized patients with mild PIH and 90 healthy maternal cases were tested and compared.Results PIH cystatin C concentration(1.61 ± 0.28)mg/Lwas significantly higher than the control group(1.23±0.32)mg/L(P0.05),while creatinine did not change significantly.PT,TT were significantly reduced(P0.05),the FIB content and the percentage of AT-III were significantly increased(P0.05)and there was no significant difference in APTT.Conclusion Patients with mild PIH have a hypercoagulable tendency and decreased renal function,which calls for due attention.

Key concepts: Cystatin C, Medicine, Internal medicine, Gastroenterology, Creatinine, Renal function, Coagulation, Clinical significance

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