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CT Diagnosis of Hepatic Focal Nodular Hyperplasia Correlated with Pathology

Wei Zhou

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Abstract

Objective:To investigate the CT findings of hepatic focal nodular hyperplasia(FNH).Methods:12 cases with pathology proved hepatic FNH underwent plain and dual-phase enhanced CT scans,the imaging features were analysed retrospectively and correlated with pathology.Results:All 12 cases of FNH had solitary globular or lobulated mass,10 cases located peripherally under the liver capsule,the diameter ranged from 2~6cm.The FNH were iso-or slightly hypo-attenuated on plain CT and marked homogeneously enhanced after contrast administration,with the density closed to that of abdominal aorta during the arterial phase,slightly higher than normal liver parenchyma in 9 cases and iso-attenuated in 3 cases during the portal venous phase.Typical central scar was showed in 4 cases and 1 case with central scar showing delayed enhancement.All of the 12 FNHs had no capsule on pathology,showing solitary and nodular mass with central fibrous scar that contained thick-wall blood vessels and bile duct proliferation.Conclusion:Typical FNH can be accurately diagnosed by CT.

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Objective:To investigate the CT findings of hepatic focal nodular hyperplasia(FNH).Methods:12 cases with pathology proved hepatic FNH underwent plain and dual-phase enhanced CT scans,the imaging features were analysed retrospectively and correlated with pathology.Results:All 12 cases of FNH had solitary globular or lobulated mass,10 cases located peripherally under the liver capsule,the diameter ranged from 2~6cm.The FNH were iso-or slightly hypo-attenuated on plain CT and marked homogeneously enhanced after contrast administration,with the density closed to that of abdominal aorta during the arterial phase,slightly higher than normal liver parenchyma in 9 cases and iso-attenuated in 3 cases during the portal venous phase.Typical central scar was showed in 4 cases and 1 case with central scar showing delayed enhancement.All of the 12 FNHs had no capsule on pathology,showing solitary and nodular mass with central fibrous scar that contained thick-wall blood vessels and bile duct proliferation.Conclusion:Typical FNH can be accurately diagnosed by CT.

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Available abstract

Objective:To investigate the CT findings of hepatic focal nodular hyperplasia(FNH).Methods:12 cases with pathology proved hepatic FNH underwent plain and dual-phase enhanced CT scans,the imaging features were analysed retrospectively and correlated with pathology.Results:All 12 cases of FNH had solitary globular or lobulated mass,10 cases located peripherally under the liver capsule,the diameter ranged from 2~6cm.The FNH were iso-or slightly hypo-attenuated on plain CT and marked homogeneously enhanced after contrast administration,with the density closed to that of abdominal aorta during the arterial phase,slightly higher than normal liver parenchyma in 9 cases and iso-attenuated in 3 cases during the portal venous phase.Typical central scar was showed in 4 cases and 1 case with central scar showing delayed enhancement.All of the 12 FNHs had no capsule on pathology,showing solitary and nodular mass with central fibrous scar that contained thick-wall blood vessels and bile duct proliferation.Conclusion:Typical FNH can be accurately diagnosed by CT.

Key concepts: Focal nodular hyperplasia, Medicine, Capsule, Liver parenchyma, Pathology, Parenchyma, Radiology, Fibrous capsule of Glisson

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