Improvement on the experiment of leaching of aspirin
Lei Zhiju
Abstract
Lei Zhiju
Abstract
Drug dissolution experiment is one of the Pharmaceutics Experiments in the courses of the Pharmaceutics and the Industrial Pharmacy,which plays an important guiding act in learnning and understanding the knowledge of drug dissolution.And in our university,we use aspirin tablet as the solid dosage form to test it’s dissolution rate in the visible area with UV-PDA Spectrophotometer.But the student’s experiment remains some certain defects,the results are generally unfavorable.We found out another better wavelength according to the relevant literature and our experiments.It is practical for students to do because of the good reproducibility and stability.
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Drug dissolution experiment is one of the Pharmaceutics Experiments in the courses of the Pharmaceutics and the Industrial Pharmacy,which plays an important guiding act in learnning and understanding the knowledge of drug dissolution.And in our university,we use aspirin tablet as the solid dosage form to test it’s dissolution rate in the visible area with UV-PDA Spectrophotometer.But the student’s experiment remains some certain defects,the results are generally unfavorable.We found out another better wavelength according to the relevant literature and our experiments.It is practical for students to do because of the good reproducibility and stability.
Key concepts: Pharmaceutics, Dissolution, Dissolution testing, Reproducibility, Aspirin, Pharmacy, Drug, Pharmacology