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Optimization the Extraction Process of Baicalin in Scutellaria Baicalensis Georgiorthogonal

Liu Chunjin

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Abstract

This paper establishes a HPLC method for determination of baicalin,and studies the various factors affecting the baicalin in ultrasonic extraction, and an orthogonal experiment is designed to optimize the ultrasonic extraction process.Ultrasonic extraction of baicalin best level is 1∶22,60%,30min,300W,baicalin yield reached 6.67%. The obtaintion of baicalin under the condition of the process is stable and efficient. The results show that the ultrasonic extraction method is simple,fast,high extraction efficiency,low energy consumption,significantly better than traditional extraction method,and has a broad application prospect.

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What this paper is about

This paper establishes a HPLC method for determination of baicalin,and studies the various factors affecting the baicalin in ultrasonic extraction, and an orthogonal experiment is designed to optimize the ultrasonic extraction process.Ultrasonic extraction of baicalin best level is 1∶22,60%,30min,300W,baicalin yield reached 6.67%. The obtaintion of baicalin under the condition of the process is stable and efficient. The results show that the ultrasonic extraction method is simple,fast,high extraction efficiency,low energy consumption,significantly better than traditional extraction method,and has a broad application prospect.

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Available abstract

This paper establishes a HPLC method for determination of baicalin,and studies the various factors affecting the baicalin in ultrasonic extraction, and an orthogonal experiment is designed to optimize the ultrasonic extraction process.Ultrasonic extraction of baicalin best level is 1∶22,60%,30min,300W,baicalin yield reached 6.67%. The obtaintion of baicalin under the condition of the process is stable and efficient. The results show that the ultrasonic extraction method is simple,fast,high extraction efficiency,low energy consumption,significantly better than traditional extraction method,and has a broad application prospect.

Key concepts: Baicalin, Extraction (chemistry), Ultrasonic sensor, Scutellaria baicalensis, Chromatography, Yield (engineering), Process (computing), Materials science

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