2012Journal of Brain and Nervous DiseasesRequires access

Curative effects of edaravone combined edaravone low molecular heparin on treating progressive cerebral infarction

Yang Ming-jia

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Abstract

Objective To discuss the curative effects and security of Edaravone combined Edaravone low molecular heparin on treating progressive cerebral infarction(PCI).Methods 100 patients with progressive cerebral infarction were divided into two groups randomly,the observation group(50cases) and control group(50cases) of the same basic treatment.The observation group were treated with Edaravone 30 mg intravenousdrip twice a day for 14d.Meanwhile,low molecular heparin sodium 5000IU per 12 hours for 7d.Control group using the aspirin 300mg/d oral for 3 days,then subsequently 100mg/d.Platelet(PLT),activated partical prothrom-plastin time(APTT)、Fibrinogen(Fg)、Neurospecific eolase(NSE) and Neural Functional Impairment Scoring were tested before and after treatment in the two groups.Results The cure rate and the effective rate of the observation group were obviously higher than those of the control group(P0.05).And without obvious advers reaction in two group.Conclusion Edaravone combined with low molecular heparin is safe and effective on progressive cerebral infarction.

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Objective To discuss the curative effects and security of Edaravone combined Edaravone low molecular heparin on treating progressive cerebral infarction(PCI).Methods 100 patients with progressive cerebral infarction were divided into two groups randomly,the observation group(50cases) and control group(50cases) of the same basic treatment.The observation group were treated with Edaravone 30 mg intravenousdrip twice a day for 14d.Meanwhile,low molecular heparin sodium 5000IU per 12 hours for 7d.Control group using the aspirin 300mg/d oral for 3 days,then subsequently 100mg/d.Platelet(PLT),activated partical prothrom-plastin time(APTT)、Fibrinogen(Fg)、Neurospecific eolase(NSE) and Neural Functional Impairment Scoring were tested before and after treatment in the two groups.Results The cure rate and the effective rate of the observation group were obviously higher than those of the control group(P0.05).And without obvious advers reaction in two group.Conclusion Edaravone combined with low molecular heparin is safe and effective on progressive cerebral infarction.

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Available abstract

Objective To discuss the curative effects and security of Edaravone combined Edaravone low molecular heparin on treating progressive cerebral infarction(PCI).Methods 100 patients with progressive cerebral infarction were divided into two groups randomly,the observation group(50cases) and control group(50cases) of the same basic treatment.The observation group were treated with Edaravone 30 mg intravenousdrip twice a day for 14d.Meanwhile,low molecular heparin sodium 5000IU per 12 hours for 7d.Control group using the aspirin 300mg/d oral for 3 days,then subsequently 100mg/d.Platelet(PLT),activated partical prothrom-plastin time(APTT)、Fibrinogen(Fg)、Neurospecific eolase(NSE) and Neural Functional Impairment Scoring were tested before and after treatment in the two groups.Results The cure rate and the effective rate of the observation group were obviously higher than those of the control group(P0.05).And without obvious advers reaction in two group.Conclusion Edaravone combined with low molecular heparin is safe and effective on progressive cerebral infarction.

Key concepts: Edaravone, Medicine, Aspirin, Cerebral infarction, Anesthesia, Fibrinogen, Heparin, Internal medicine

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