Distribution of pathogenic bacteria causing clinical infection and investigation of drug resistance during 2007-2009

OBJECTIVE To analyze the pathogens in tumor patients with nosocomial infection and their resistance.In order to provide evidence for the guidance of clinical rational administration and to decrease the nosocomial infection.METHODS A total of 980 strains of clinical pathogenic bacteria isolated by bacteriology laboratory and drug resistance from 2007 to 2009 were analyzed.RESULTS The main pathogenic bacteria were the Gram-negative bacilli(50.7%).And the second pathogenic bacteria were the fungi(34.3%).The Gram-positive cocci(15.0%) The constituent ratio of the detection in Gram-negative bacilli ncreased year by year in the last three years,while the detection in Gram-positive cocci decreased.The 3-year average rate of drug resistance of Gram-negative bacilli to ampicillin,piperacillin,gentamicin,tobramycin were over 70.0%,and the 3-year average rates of drug resistance of Gram-positive cocci to ampicillin and ciprofloxacin hydrochloride were also over 70.0%.The drug resistance rate to amphotericin B and nystatin were 6.0%.CONCLUSION We should think highly of etiological detection and monitoring of drug resistance in pathogen nosocomial infections in tumor patients in order to control the infections effectively.