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2000•Journal of Huaihai MedicineRequires access

A study on the Interruption of HBV transmission from mother to newborn Infants

WU Liangxia

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Abstract

Objective To investigate the effects of HBIg and hepatitis B vaccine on the prevention of HBV transmission from mother to newborn infants. Methods Newborn infants whose mothers were HBsAg (+ ), HBeAg(+) and HBcAb(+) were treated with HBIg and hepatitis B vaccine (Group I),while the newborn infants whose mother were HBsAg(+),HBeAb(+) and HBcAb(+ ) were injected hepatitis B vaccine only (Group Ⅱ). HBsAg and HBsAb were detected at 6, 9, 12 month after birth. Results In group I,Infants' HBsAg and HBsAb positive rate were 14. 29% and 71. 42% respectively, while in group Ⅱ,were 0. 0% and 86. 67%. Conclusion Intrauterine infection is responsible to the failing inoculation of hepatitis B vaccine.

About this research paper

What this paper is about

Objective To investigate the effects of HBIg and hepatitis B vaccine on the prevention of HBV transmission from mother to newborn infants. Methods Newborn infants whose mothers were HBsAg (+ ), HBeAg(+) and HBcAb(+) were treated with HBIg and hepatitis B vaccine (Group I),while the newborn infants whose mother were HBsAg(+),HBeAb(+) and HBcAb(+ ) were injected hepatitis B vaccine only (Group Ⅱ). HBsAg and HBsAb were detected at 6, 9, 12 month after birth. Results In group I,Infants' HBsAg and HBsAb positive rate were 14. 29% and 71. 42% respectively, while in group Ⅱ,were 0. 0% and 86. 67%. Conclusion Intrauterine infection is responsible to the failing inoculation of hepatitis B vaccine.

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Available abstract

Objective To investigate the effects of HBIg and hepatitis B vaccine on the prevention of HBV transmission from mother to newborn infants. Methods Newborn infants whose mothers were HBsAg (+ ), HBeAg(+) and HBcAb(+) were treated with HBIg and hepatitis B vaccine (Group I),while the newborn infants whose mother were HBsAg(+),HBeAb(+) and HBcAb(+ ) were injected hepatitis B vaccine only (Group Ⅱ). HBsAg and HBsAb were detected at 6, 9, 12 month after birth. Results In group I,Infants' HBsAg and HBsAb positive rate were 14. 29% and 71. 42% respectively, while in group Ⅱ,were 0. 0% and 86. 67%. Conclusion Intrauterine infection is responsible to the failing inoculation of hepatitis B vaccine.

Key concepts: Medicine, HBsAg, HBeAg, Hepatitis B vaccine, Transmission (telecommunications), Hepatitis B, Virology, Hepatitis B immune globulin

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