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2007•Journal of psychiatryRequires access

A comparative of study paroxetine in the treatment of depression with physical symptoms

Zhang Zhong-ron

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Abstract

Objective To study the effect and safty of paroxetine in the treatment of depression with physical symptoms.Methods A total of 80 depressive patients were divided into control group treated by amitriptyline and study group treated by paroxetine for 6 weeks of treatment.The effect was evaluated with HAMD and CGI and the adverse effects were evaluated with TESS.Results Scores of HAMD and CGI-SI had significant differences before and after treatment in two groups,but the difference between two groups was not found in decreased scores.Conclusion Paroxetine is effective for depression with physical symptoms.

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What this paper is about

Objective To study the effect and safty of paroxetine in the treatment of depression with physical symptoms.Methods A total of 80 depressive patients were divided into control group treated by amitriptyline and study group treated by paroxetine for 6 weeks of treatment.The effect was evaluated with HAMD and CGI and the adverse effects were evaluated with TESS.Results Scores of HAMD and CGI-SI had significant differences before and after treatment in two groups,but the difference between two groups was not found in decreased scores.Conclusion Paroxetine is effective for depression with physical symptoms.

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Available abstract

Objective To study the effect and safty of paroxetine in the treatment of depression with physical symptoms.Methods A total of 80 depressive patients were divided into control group treated by amitriptyline and study group treated by paroxetine for 6 weeks of treatment.The effect was evaluated with HAMD and CGI and the adverse effects were evaluated with TESS.Results Scores of HAMD and CGI-SI had significant differences before and after treatment in two groups,but the difference between two groups was not found in decreased scores.Conclusion Paroxetine is effective for depression with physical symptoms.

Key concepts: Paroxetine, Hamd, Depression (economics), Amitriptyline, Significant difference, Adverse effect, Psychology, Medicine

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