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Epidemiologic Survey of First Case with Highly Pathogenic Avian Influenza Virus(H5N1) in Shenzhen

Shunxiang Zhang

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Abstract

OBJECTIVE To analyze possible source of infection under the condition of no exposure to sick or dead poultry and provide scientific evidence for further prevention and control of avian influenza by epidemiologic investigation of the first case infected with highly pathogenic avian influenza virus(H5N1) in Shenzhen.METHODS Descriptive epidemiology,emergency surveillance,ELISA and real-time PCR(RT-PCR) were used for analysis and diagnosis concerning the first H5N1 response.RESULTS The first case infected with H5N1 in Shenzhen was confirmed.But history of exposure to infected poultry,pneumonia of unknown etiology from close contacts and evidence of human-to-human transmission were not found.CONCLUSIONS The first H5N1 patient in Shenzhen is not a case induced by human-to-human transmission and the infection source might be from the farmers′ market.

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What this paper is about

OBJECTIVE To analyze possible source of infection under the condition of no exposure to sick or dead poultry and provide scientific evidence for further prevention and control of avian influenza by epidemiologic investigation of the first case infected with highly pathogenic avian influenza virus(H5N1) in Shenzhen.METHODS Descriptive epidemiology,emergency surveillance,ELISA and real-time PCR(RT-PCR) were used for analysis and diagnosis concerning the first H5N1 response.RESULTS The first case infected with H5N1 in Shenzhen was confirmed.But history of exposure to infected poultry,pneumonia of unknown etiology from close contacts and evidence of human-to-human transmission were not found.CONCLUSIONS The first H5N1 patient in Shenzhen is not a case induced by human-to-human transmission and the infection source might be from the farmers′ market.

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Available abstract

OBJECTIVE To analyze possible source of infection under the condition of no exposure to sick or dead poultry and provide scientific evidence for further prevention and control of avian influenza by epidemiologic investigation of the first case infected with highly pathogenic avian influenza virus(H5N1) in Shenzhen.METHODS Descriptive epidemiology,emergency surveillance,ELISA and real-time PCR(RT-PCR) were used for analysis and diagnosis concerning the first H5N1 response.RESULTS The first case infected with H5N1 in Shenzhen was confirmed.But history of exposure to infected poultry,pneumonia of unknown etiology from close contacts and evidence of human-to-human transmission were not found.CONCLUSIONS The first H5N1 patient in Shenzhen is not a case induced by human-to-human transmission and the infection source might be from the farmers′ market.

Key concepts: Influenza A virus subtype H5N1, Highly pathogenic, Transmission (telecommunications), Virology, Epidemiology, Avian influenza virus, Etiology, Transmission and infection of H5N1

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Epidemiologic Survey of First Case with Highly Pathogenic Avian Influenza Virus(H5N1) in Shenzhen — Research Paper | ScholarLens