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Immunophenotype Analysis of Blood T Lymphocytes in 289 Patients with Advanced Malignant Tumor

Mei Li

Abstract

Objective:To analyze the character,influence factors and clinical value of T lymphocyte subgroups in peripheral blood of patients with advanced malignant tumor.Methods:T lymphocyte subgroups in peripheral blood of 289 patients with advanced malignant tumor were detected by flow cytometry.Results:1)CD3 +T lymphocyte 59.07±14.28,CD4 +T lymphocyte 24.70±10.70,CD8 +T lymphocyte 33.45±12.72,CD4/CD8 0.89±0.56;2)The age and gender didn's influence the value of cluster of differentiation(P0.05)except CD3 which was influenced by gender of patients(P=0.003).Conclusion:The function of cellular immunity is abnormal in patients with advanced malignant tumor.

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Key concepts: Medicine, CD8, Immunophenotyping, Peripheral blood, Lymphocyte, Flow cytometry, Lymphocyte subsets, CD3