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2004•Journal of Zhenjiang Medical CollegeRequires access

The Effect of Iabiatae on Renal Injury in Rats with Acute Necrotizing Pancreatitis

Yajun Sun

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Abstract

Objective: To explore the effects of labiatae on the changes of renal injury in rats with acute necrotizing pancreatiais(ANP). Methods: A total of 96 rats were randomly divided into control group (C),pancreatitis group (P) and treatment group (T). The model of ANP was established by injection of 5% sodium taurocholate into the pancreatic capsule. The number of neutrophils infiltrating in the kidney and the pathological changes were observed at 2 h and 12 h after induction of ANP. Results: Comparing with group C, the renal pathological changes and the neutrophils infiltration in the kidney were significant at 2 h and 12 h after ANP in group P (P0.001). Contrast with group P, the renal pathological changes and neutrophils infiltration were alleviated significantly(P0.05) at 2 h and 12 h in group T. Conclusion: The labiatae had the effects on protecting the ANP renal injury. [

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Objective: To explore the effects of labiatae on the changes of renal injury in rats with acute necrotizing pancreatiais(ANP). Methods: A total of 96 rats were randomly divided into control group (C),pancreatitis group (P) and treatment group (T). The model of ANP was established by injection of 5% sodium taurocholate into the pancreatic capsule. The number of neutrophils infiltrating in the kidney and the pathological changes were observed at 2 h and 12 h after induction of ANP. Results: Comparing with group C, the renal pathological changes and the neutrophils infiltration in the kidney were significant at 2 h and 12 h after ANP in group P (P0.001). Contrast with group P, the renal pathological changes and neutrophils infiltration were alleviated significantly(P0.05) at 2 h and 12 h in group T. Conclusion: The labiatae had the effects on protecting the ANP renal injury. [

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Available abstract

Objective: To explore the effects of labiatae on the changes of renal injury in rats with acute necrotizing pancreatiais(ANP). Methods: A total of 96 rats were randomly divided into control group (C),pancreatitis group (P) and treatment group (T). The model of ANP was established by injection of 5% sodium taurocholate into the pancreatic capsule. The number of neutrophils infiltrating in the kidney and the pathological changes were observed at 2 h and 12 h after induction of ANP. Results: Comparing with group C, the renal pathological changes and the neutrophils infiltration in the kidney were significant at 2 h and 12 h after ANP in group P (P0.001). Contrast with group P, the renal pathological changes and neutrophils infiltration were alleviated significantly(P0.05) at 2 h and 12 h in group T. Conclusion: The labiatae had the effects on protecting the ANP renal injury. [

Key concepts: Pathological, Infiltration (HVAC), Medicine, Kidney, Renal injury, Necrotizing pancreatitis, Pancreatitis, Acute pancreatitis

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