Clinical analysis of recurrent hemorrhage after craniotomy in 162 patients with hypertensive cerebral hemorrhage

Objectives To analyze the risk factors for recurrent hemorrhage after craniotomy in patients with hypertensive cerebral hemorrhage(HCH).Methods Clinical data of 162 HCH patients undergone surgery were retrospectively analyzed.We focused on the surgery methods,results,follow-up and multiple regression analyses were carried out on risk factors (gender,age,duration of hypertension,history of diabetes mellitus and hypercholesterolemia,site and volume of hemorrhage and post-surgical systolic and diastolic pressure) for recurrent hemorrhage after craniotomy in patients with HCH.Results Hypertension appeared on nineteen 19 after surgery,recurrent hemorrhage appeared on 24 patients and the rate of recurrent hemorrhage was 14.8% (24 /162),16 died and the case fatality was 9.8% (16 /162).After followed up for 6 months,recurrent hemorrhage appeared on 1 patient and he needed surgery again.Multiple regression analysis indicated that duration of hypertension (P=0.036,OR=1.086),history of diabetes mellitus (P=0.026,OR= 1.100) and post-surgical systolic pressure (P=0.039,OR=1.218) had positive correlation with recurrent hemorrhage after craniotomy in patients with HCH.Conclusions Risk factors for recurrent hemorrhage after craniotomy in patients with HCH are diabetes,long-term hypertension and higher post-surgical systolic pressure.