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2010•Laboratory Medicine and ClinicRequires access

Evaluation of three methods for the detection of syphilis

LI Zhen-min

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Abstract

Objective To explore the value of rapid plasma reagin test (RPR),enzyme-linked immunosorbent assay (ELISA) and treponema pallidum particle assay(TPPA)in the diagnosis of syphilis.Methods The serums of 228 syphilitic cases were detected by RPR,ELISA and TPPA.Results The sensitivity was 73.0 % for RPR,97.4% for ELISA,and 99.7 % for TPPA.The detection result of RPR had a significant difference compared with the detection results of ELISA and TPPA,while there was no significant difference between ELISA and TPPA.Conclusion Because each method of syphilic detection has merits and demerits,the selection of methed should be on the basis of check purpose.

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What this paper is about

Objective To explore the value of rapid plasma reagin test (RPR),enzyme-linked immunosorbent assay (ELISA) and treponema pallidum particle assay(TPPA)in the diagnosis of syphilis.Methods The serums of 228 syphilitic cases were detected by RPR,ELISA and TPPA.Results The sensitivity was 73.0 % for RPR,97.4% for ELISA,and 99.7 % for TPPA.The detection result of RPR had a significant difference compared with the detection results of ELISA and TPPA,while there was no significant difference between ELISA and TPPA.Conclusion Because each method of syphilic detection has merits and demerits,the selection of methed should be on the basis of check purpose.

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Available abstract

Objective To explore the value of rapid plasma reagin test (RPR),enzyme-linked immunosorbent assay (ELISA) and treponema pallidum particle assay(TPPA)in the diagnosis of syphilis.Methods The serums of 228 syphilitic cases were detected by RPR,ELISA and TPPA.Results The sensitivity was 73.0 % for RPR,97.4% for ELISA,and 99.7 % for TPPA.The detection result of RPR had a significant difference compared with the detection results of ELISA and TPPA,while there was no significant difference between ELISA and TPPA.Conclusion Because each method of syphilic detection has merits and demerits,the selection of methed should be on the basis of check purpose.

Key concepts: Rapid plasma reagin, Syphilis, Significant difference, Treponema, Medicine, Syphilis Serodiagnosis, Virology, Internal medicine

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