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Clinic Significance and Variation of N-terminal Pro-brain Natriuretic Peptide and Brain Batriuretic Peptide in Children with Kawasaki Disease

Liu Yaqiu

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Abstract

Objective To explore the change and value of plasma brain natriuretic peptide(BNP) and N-terminal pro-brain natriuretic peptide(NT-proBNP) in children with Kawasaki Disease(KD). Methods 51 KD patients,aged from 4 months to 75 months,and 15 patients with acute upper respiratory infection as control were enrolled into the experiment.Plasma concentrations of BNP and NT-proBNP were measured by ELISA. Results The levels of plasma NT-pro BNP and BNP were significantly higher in KD patients than those of control group;plasma NT-pro BNP level was significantly higher in iKD than that of control group. Conclusion The data indicated that plasma BNP and NT-pro BNP could be used as useful biochemical markers in diagnosis of KD,and plasma NT-proBNP is more valuable in diagnosis of iKD.

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What this paper is about

Objective To explore the change and value of plasma brain natriuretic peptide(BNP) and N-terminal pro-brain natriuretic peptide(NT-proBNP) in children with Kawasaki Disease(KD). Methods 51 KD patients,aged from 4 months to 75 months,and 15 patients with acute upper respiratory infection as control were enrolled into the experiment.Plasma concentrations of BNP and NT-proBNP were measured by ELISA. Results The levels of plasma NT-pro BNP and BNP were significantly higher in KD patients than those of control group;plasma NT-pro BNP level was significantly higher in iKD than that of control group. Conclusion The data indicated that plasma BNP and NT-pro BNP could be used as useful biochemical markers in diagnosis of KD,and plasma NT-proBNP is more valuable in diagnosis of iKD.

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Available abstract

Objective To explore the change and value of plasma brain natriuretic peptide(BNP) and N-terminal pro-brain natriuretic peptide(NT-proBNP) in children with Kawasaki Disease(KD). Methods 51 KD patients,aged from 4 months to 75 months,and 15 patients with acute upper respiratory infection as control were enrolled into the experiment.Plasma concentrations of BNP and NT-proBNP were measured by ELISA. Results The levels of plasma NT-pro BNP and BNP were significantly higher in KD patients than those of control group;plasma NT-pro BNP level was significantly higher in iKD than that of control group. Conclusion The data indicated that plasma BNP and NT-pro BNP could be used as useful biochemical markers in diagnosis of KD,and plasma NT-proBNP is more valuable in diagnosis of iKD.

Key concepts: Kawasaki disease, Medicine, Natriuretic peptide, Brain natriuretic peptide, N-terminal pro-Brain Natriuretic Peptide, Internal medicine, Plasma levels, Plasma concentration

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Clinic Significance and Variation of N-terminal Pro-brain Natriuretic Peptide and Brain Batriuretic Peptide in Children with Kawasaki Disease — Research Paper | ScholarLens