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Differential potentials of human mesenchymal stem cells derived from bone marrow.

Jinfang Zhang, Li Guo, Yaou Zhang, Hsiang‐Fu Kung

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Abstract

Human mesenchymal stem cells(hMSCs) are multipotent cells which can differentiate into many different types of cells such as osteoblast,adipocyte,chondrocyte.In our study,we isolated MSCs from human bone marrow and their differential potentials were investigated.The osteogenic and adipogenic differentiation were induced through staining and marker gene assay.In conclusion,MSCs derived from human bone marrow were abundant and multipotent.Therefore,they maybe initiate a new era where MSCs can broadly be used in clinical application.

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What this paper is about

Human mesenchymal stem cells(hMSCs) are multipotent cells which can differentiate into many different types of cells such as osteoblast,adipocyte,chondrocyte.In our study,we isolated MSCs from human bone marrow and their differential potentials were investigated.The osteogenic and adipogenic differentiation were induced through staining and marker gene assay.In conclusion,MSCs derived from human bone marrow were abundant and multipotent.Therefore,they maybe initiate a new era where MSCs can broadly be used in clinical application.

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Available abstract

Human mesenchymal stem cells(hMSCs) are multipotent cells which can differentiate into many different types of cells such as osteoblast,adipocyte,chondrocyte.In our study,we isolated MSCs from human bone marrow and their differential potentials were investigated.The osteogenic and adipogenic differentiation were induced through staining and marker gene assay.In conclusion,MSCs derived from human bone marrow were abundant and multipotent.Therefore,they maybe initiate a new era where MSCs can broadly be used in clinical application.

Key concepts: Mesenchymal stem cell, Multipotent Stem Cell, Human bone, Adipogenesis, Bone marrow, Stem cell transplantation for articular cartilage repair, Cell biology, Osteoblast

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