Clinical Research of Yiqitongyu Method in Protection Intestinal Barrier in Patients with Multiple Organ Dysfunction Syndrome

Objective: To observe the validity of Yiqitongyu method in protection intestinal barrier of patients with multiple organ dysfunction syndrome(MODS) and its influence to systemic inflammatory response.Methods: 40 patients with MODS were divided into 2 groups.On the basis of the routine therapies in 2 groups.The experimental group was added the Yiqitongyu Herbs.Some indices were compared in 2 groups including the gastrointestinal function score,the diamine oxidase(DAO),the D-lactic acid,the endotoxin,the C reactive protein(CRP), the APACHE Ⅱ score and the Marshall score before therapy,3 days,7 days and 14 days after therapy.Results: 3 days after therapy,there was a significantly difference in the DAO in 2 groups.7 days after therapy,there were some obvious differences in the gastrointestinal function score and the D-lactic acid between 2 groups.14 days after therapy,the endotoxin and the CRP were significantly different in the experiment group comparing the control group.However,the APACHE Ⅱ score and the Marshall score in the experiment group were no remarkable differences when they compared with the control group.Conclusion: Yiqitongyu method could improve gastrointestinal function and reduce systemic inflammatory response.