The Study of Multidetector CT Perfusion in Primary Liver Carcinoma
Guan Yong-song
Abstract
Guan Yong-song
Abstract
Objective:To study the parameters of CT perfusion imaging of primary liver carcinoma(PLC).Methods:CT perfusion imaging of liver was obtained in 36 individuals,including 23 patients with PLC and 13 control subjects.Liver perfusion parameters such as hepatic arterial perfusion(HAP),hepatic portal perfuiosn (HPP),total liver perfusion(TLP)and hepatic arterial perfusion index(HAPI)were calculated,and the change of the hemodynamics was estimated.Results:Compared with the control group,HAP(0.45±0.26ml·min~ -1 ·ml~ -1 versus 0.19±0.06ml·min~ -1 ·ml~ -1 ,P=0.001)and HAPI(0.61±0.21 versus 0.23±0.08,P=0.000)in PLC group increased significantly,HPP(0.31±0.22 ml·min~ -1 ·ml~ -1 versus 0.66±0.20ml·min~ -1 ·ml~ -1 ,P=0.000)decreased significantly,TLP(0.76±0.34ml·min~ -1 ·ml~ -1 versus 0.86±0.20ml·min~ -1 ·ml~ -1 ,P=0.329) did not differ between the two groups.Conclusion:CT perfusion imaging could be a new method to evaluate the blood supply of PLC.
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Objective:To study the parameters of CT perfusion imaging of primary liver carcinoma(PLC).Methods:CT perfusion imaging of liver was obtained in 36 individuals,including 23 patients with PLC and 13 control subjects.Liver perfusion parameters such as hepatic arterial perfusion(HAP),hepatic portal perfuiosn (HPP),total liver perfusion(TLP)and hepatic arterial perfusion index(HAPI)were calculated,and the change of the hemodynamics was estimated.Results:Compared with the control group,HAP(0.45±0.26ml·min~ -1 ·ml~ -1 versus 0.19±0.06ml·min~ -1 ·ml~ -1 ,P=0.001)and HAPI(0.61±0.21 versus 0.23±0.08,P=0.000)in PLC group increased significantly,HPP(0.31±0.22 ml·min~ -1 ·ml~ -1 versus 0.66±0.20ml·min~ -1 ·ml~ -1 ,P=0.000)decreased significantly,TLP(0.76±0.34ml·min~ -1 ·ml~ -1 versus 0.86±0.20ml·min~ -1 ·ml~ -1 ,P=0.329) did not differ between the two groups.Conclusion:CT perfusion imaging could be a new method to evaluate the blood supply of PLC.
Key concepts: Medicine, Perfusion, Arterial perfusion, Perfusion scanning, Nuclear medicine, Hemodynamics, Carcinoma, Liver perfusion