Contrast-Enhanced MRI Combined Diffusion-Weighted Image on Identification of Benign and Malignant Breast Lesions

Objective:To explore the diagnostic value of dynamic contrast-enhanced MRI time-signal intensity curve(TIC) combined diffusion-weighted imaging(DWI) in distinguishing the benign and malignant breast lesions.Methods:Forty cases(41 lesions) with pathologically confirmed breast lesions had MRI T1WI,T2WI,DWI(b value = 800 s/mm2)and dynamic contrast-enhanced MR scan.The signal intensity,apparent diffusion coefficient(ADC) values,enhanced TIC of the lesions were retrospectively analyzed.Results The types of TIC in all 41 lesions(40 cases) included type Ⅰ curve(10 benign and malignant 0);Ⅱcurve(10 benign,4 malignant);III curve(3 benign,malignant 15);IV curve(2 benign lesions).The ADC values of 24 lesions 1.2×10-3mm2/s(21 benign,3 malignant);ADC values of 18 lesions 1.22×10-3 mm2/s(16 malignant and 2 benign).Conclusion: Dynamic contrast-enhanced MRI TIC combined DWI has high sensitivity and specificity in diagnosing breast lesions.The type of TIC and the value of ADC play important roles in differentiating benign and malignant breast lesions.