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The Value of Diffusion Weighted Imaging in Differentiating the Benign and Malignant Tumors of Breast

Yi-gai He

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Abstract

Objective:To study the value of diffusion weighted imaging in differentiating the benign and malignant tumors of breast.Methods:Select 20 normal breast,22 benign breast lesions and 32 patients with breast malignancy as research objects,using 1.5T MRI scanner,line T1WI,T2WI and fat-suppressed,DWI and dynamic contrast-enhanced imaging and delayed enhancement scan were underwent on them.b values in the DWI were taken 200,500,800,1000,l200,1500,2000.Measuring the ADC value of normal breast,benign and malignant lesions,and statistically analyzed were underwent on each other.Results:(1) Malignant breast lesions have high signal on DWI imaging,and benign lesions showed a slightly higher signal;(2) In each group,the ADC values changing with different b values,in the condition of same b value,the ADC values of malignant group and benign group,malignant group and normal group have significantly difference,benign group and normal group,have no difference;(3) With b value from 200 rose to 2000,the sensitivity and specificity of ADC values in differentiating the benign and malignant lesions,changing from low to high,and high to low,the highest appearing in 1000,were 91.2%,89.3%,the ADC threshold value was 1.22.Conclusion:DWI combined with ADC value measurement,have high clinical value in differentiating benign and malignant breast lesions.

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Objective:To study the value of diffusion weighted imaging in differentiating the benign and malignant tumors of breast.Methods:Select 20 normal breast,22 benign breast lesions and 32 patients with breast malignancy as research objects,using 1.5T MRI scanner,line T1WI,T2WI and fat-suppressed,DWI and dynamic contrast-enhanced imaging and delayed enhancement scan were underwent on them.b values in the DWI were taken 200,500,800,1000,l200,1500,2000.Measuring the ADC value of normal breast,benign and malignant lesions,and statistically analyzed were underwent on each other.Results:(1) Malignant breast lesions have high signal on DWI imaging,and benign lesions showed a slightly higher signal;(2) In each group,the ADC values changing with different b values,in the condition of same b value,the ADC values of malignant group and benign group,malignant group and normal group have significantly difference,benign group and normal group,have no difference;(3) With b value from 200 rose to 2000,the sensitivity and specificity of ADC values in differentiating the benign and malignant lesions,changing from low to high,and high to low,the highest appearing in 1000,were 91.2%,89.3%,the ADC threshold value was 1.22.Conclusion:DWI combined with ADC value measurement,have high clinical value in differentiating benign and malignant breast lesions.

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Available abstract

Objective:To study the value of diffusion weighted imaging in differentiating the benign and malignant tumors of breast.Methods:Select 20 normal breast,22 benign breast lesions and 32 patients with breast malignancy as research objects,using 1.5T MRI scanner,line T1WI,T2WI and fat-suppressed,DWI and dynamic contrast-enhanced imaging and delayed enhancement scan were underwent on them.b values in the DWI were taken 200,500,800,1000,l200,1500,2000.Measuring the ADC value of normal breast,benign and malignant lesions,and statistically analyzed were underwent on each other.Results:(1) Malignant breast lesions have high signal on DWI imaging,and benign lesions showed a slightly higher signal;(2) In each group,the ADC values changing with different b values,in the condition of same b value,the ADC values of malignant group and benign group,malignant group and normal group have significantly difference,benign group and normal group,have no difference;(3) With b value from 200 rose to 2000,the sensitivity and specificity of ADC values in differentiating the benign and malignant lesions,changing from low to high,and high to low,the highest appearing in 1000,were 91.2%,89.3%,the ADC threshold value was 1.22.Conclusion:DWI combined with ADC value measurement,have high clinical value in differentiating benign and malignant breast lesions.

Key concepts: Medicine, Malignancy, Diffusion MRI, Radiology, Breast cancer, Significant difference, Effective diffusion coefficient, Nuclear medicine

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