Clinical Significance of Serum Cystatin C in Treating Elderly Hypertensive Renal Damage

Objective To study the application value of serum cystatin C(CysC) in hypertensive patients with impaired renal function.Methods Tested the levels of serum CysC,Creatinine(Cr) and uric acid(UA) and made a comparison between CysC and UA in patients with different Cr.Results The difference of CysC in patients with different Cr was significant(P0.05);the difference of UA between the patients with normal Cr and the other three groups was significant(P0.05);the difference of UA between the other three groups was not significant(P0.05).In the patients with normal Cr,there were 35 patients with normal CysC,20 patients with CysC increasing,the difference between them was also significant(P0.05).After renal protective treatment such as controlling blood pressure,improving renal blood flow,the levels of Cr and CysC all had an obvious decrease than before(P0.05).Conclusion A sensitive endogenous indicator for early hypertensive renal impairment,serum CysC plays a very important role in early diagnosis of hypertensive renal injury,assessment of renal dysfunction and judgment of therapeutic effect.