2004•Xinxueguan kangfu yixue zazhiRequires access
Clinical investigation of perindopril combined with metoprlol in treating patients with congestive heart failure
Chen Gan, WU Ji-xiong
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Abstract
Objective: To investigate the influence of perindopril combined with metoprlol on the cardiac function, heart rate, heart chest ratio and left ventricular ejection fraction (LVEF) in patients with congestive heart failure (CHF). Methods: Sixty patients with CHF were divided into two groups. The perindopril and metoprlol treatments were on the basis of conserved therapy in therapeutic group. Control group was treat with conserved therapy and perindopril. Both groups were treated for six weeks. Results: In the therapeutic group, the heart rate slowed, the heart chest ratio, blood pressure decrased and the LVEF increased after treatment (P0. 05). However in the control group, the above stated parameters were not significant change after treatment. Above stated parameters were significant difference between two groups (P0. 05). Conclusion: Perindopril combined with metoprlol can decrease heart rate, blood pressure and heart chest ratio, and raise LVEF in patients with CHF.