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2004•Sichuan Mental HealthRequires access

A comparative study of mirtazapine and fluoxetine for depressive patients

DI Liangbao

Open publisher page 2 citations

Abstract

Objective The aim of this study was to determine the efficacy and safety of mirtazapine for the depressive patients.Methods A controlled study was carried out between 61 patients who met the CCMD-3 criteriaon of major depression and depressed episode.The 31 of total patients were treated with mirtazapine and the others were treated with fluoxetine for 6 weeks.The efficacy was assessed by Hamilton depression rating scale(HAMD) and the safety was assessed by treatment emergent sympton scale(TESS). Results After 6 weeks treatment,the efficacy rate of the mirtazapine group and the fluoxetine group were 78% and 77%,respectively.The results have no remarkable differences in two groups(P0.05).There were rapid response and minimal side effects in mirtazapine group.Conclusion Mirtazapine is an effective and safe antidepressant.

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What this paper is about

Objective The aim of this study was to determine the efficacy and safety of mirtazapine for the depressive patients.Methods A controlled study was carried out between 61 patients who met the CCMD-3 criteriaon of major depression and depressed episode.The 31 of total patients were treated with mirtazapine and the others were treated with fluoxetine for 6 weeks.The efficacy was assessed by Hamilton depression rating scale(HAMD) and the safety was assessed by treatment emergent sympton scale(TESS). Results After 6 weeks treatment,the efficacy rate of the mirtazapine group and the fluoxetine group were 78% and 77%,respectively.The results have no remarkable differences in two groups(P0.05).There were rapid response and minimal side effects in mirtazapine group.Conclusion Mirtazapine is an effective and safe antidepressant.

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Available abstract

Objective The aim of this study was to determine the efficacy and safety of mirtazapine for the depressive patients.Methods A controlled study was carried out between 61 patients who met the CCMD-3 criteriaon of major depression and depressed episode.The 31 of total patients were treated with mirtazapine and the others were treated with fluoxetine for 6 weeks.The efficacy was assessed by Hamilton depression rating scale(HAMD) and the safety was assessed by treatment emergent sympton scale(TESS). Results After 6 weeks treatment,the efficacy rate of the mirtazapine group and the fluoxetine group were 78% and 77%,respectively.The results have no remarkable differences in two groups(P0.05).There were rapid response and minimal side effects in mirtazapine group.Conclusion Mirtazapine is an effective and safe antidepressant.

Key concepts: Mirtazapine, Hamd, Fluoxetine, Antidepressant, Depression (economics), Rating scale, Medicine, Hamilton depression scale

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