Relationship between levels of plasma homocysteine and oxidative LDL in cerebral infarction patients

Objective To provide theoretical basis for prevention and treatment of cerebral infarction by determining the levels of plasma homocysteine(Hcy)and oxidative low density lipoprotein(ox-LDL)and their relationship.Methods 60 patients with cerebral infarction and 32 healthy controls were selected.Hcy and ox-LDL of two groups were determined with ELISA method.Results The levels of homocysteine and ox-LDL in cerebral inforction groups(23.25 ±3.74μmol/ L,711.45 ±128.01μmol/ L) were significantly higher than that control groups(10.82±3.55μmol/ L,406.30±100.04μg/ L) respectively.A significant positive correlation was found between level of homocysteine and ox-DL in cerebral infarction cases(r = 0.826,P0.01).Conclusion Homocystenie and ox-LDLhave involved in the pathogenesis of cerebral infarction.