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2013•The Chinese Journal of DermatovenereologyRequires access

Clinical Observation of 50 Psoriasis Vulgaris Treated with Narrow-band Ultraviolet B and Acitretin

HE Qiu-bo

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Abstract

Objective To observe the clinical efficacy and security of Narrow-band Ultraviolet B (NB-UVB) combined with Acitretin A in treating patients with psoriasis vulgaris. Methods 100 cases were given acitretin orally (10 mg per time, twice a day)and randomly divided into two groups, meanwhile, the patients of treatment group were treated by NB-UVB(three times per week), total treatment time was 8 weeks,its efficacy was observed and followed up for 6 months.Results The effective rate in treating group was 96.00% and control group was 44.00%, there were significant difference between them(P0.01). The treatment group had pigmentation, dry desquamation, itching and other adverse reactions which could be relieved by symptomatic treatment. Conclusion NB-UVB combined with acitretin in treating patients with psoriasis vulgaris is more effective and safe.

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What this paper is about

Objective To observe the clinical efficacy and security of Narrow-band Ultraviolet B (NB-UVB) combined with Acitretin A in treating patients with psoriasis vulgaris. Methods 100 cases were given acitretin orally (10 mg per time, twice a day)and randomly divided into two groups, meanwhile, the patients of treatment group were treated by NB-UVB(three times per week), total treatment time was 8 weeks,its efficacy was observed and followed up for 6 months.Results The effective rate in treating group was 96.00% and control group was 44.00%, there were significant difference between them(P0.01). The treatment group had pigmentation, dry desquamation, itching and other adverse reactions which could be relieved by symptomatic treatment. Conclusion NB-UVB combined with acitretin in treating patients with psoriasis vulgaris is more effective and safe.

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Available abstract

Objective To observe the clinical efficacy and security of Narrow-band Ultraviolet B (NB-UVB) combined with Acitretin A in treating patients with psoriasis vulgaris. Methods 100 cases were given acitretin orally (10 mg per time, twice a day)and randomly divided into two groups, meanwhile, the patients of treatment group were treated by NB-UVB(three times per week), total treatment time was 8 weeks,its efficacy was observed and followed up for 6 months.Results The effective rate in treating group was 96.00% and control group was 44.00%, there were significant difference between them(P0.01). The treatment group had pigmentation, dry desquamation, itching and other adverse reactions which could be relieved by symptomatic treatment. Conclusion NB-UVB combined with acitretin in treating patients with psoriasis vulgaris is more effective and safe.

Key concepts: Acitretin, Medicine, Psoriasis, Ultraviolet b, Desquamation, Dermatology, Itching, Adverse effect

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