2012•Chemical ResearchRequires access

Study on interaction between naphhalimide-polyamine conjugates and DNA by spectrometry

Chaojie Wang

Abstract

The interaction between naphthalimide-polyamine conjugates 1-3 and DNA was investigated by fluorimetry,and the intercalation of compounds 1-3 into DNA was examined.Results show that all the three kinds of tested naphthalimide-polyamine conjugates are able to intercalate into DNA and can act as intercalating agents of DNA.

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Available abstract

Key concepts: Intercalation (chemistry), Polyamine, Conjugate, Chemistry, DNA, Combinatorial chemistry, Mass spectrometry, Biochemistry