2009China Practical MedicineRequires access

Pharmacology Research Advance of Sophora Alkaloids

Liu Xue-hu

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Abstract

Sophora alkaloids,isolated from Leguminosae Sophora flavescens Ait.,are considered to be the main effective component,which are a class of compounds of matridine-15-ketone basic chemical structure.Sophora alkaloids belong to quinolizidine,which molecular skeleton can be seen as two molecules of quinolizidine fusion.They have ranous pharmacolog fun ction such as regulating blood lipid,anti-arrhythmic,anti-tumor,anti-liver fibrosis,immunity-regulation and so,and they have been applied in clinical widely.In the article we make an outline on the pharmacology research advance of Sophora alkaloids.

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What this paper is about

Sophora alkaloids,isolated from Leguminosae Sophora flavescens Ait.,are considered to be the main effective component,which are a class of compounds of matridine-15-ketone basic chemical structure.Sophora alkaloids belong to quinolizidine,which molecular skeleton can be seen as two molecules of quinolizidine fusion.They have ranous pharmacolog fun ction such as regulating blood lipid,anti-arrhythmic,anti-tumor,anti-liver fibrosis,immunity-regulation and so,and they have been applied in clinical widely.In the article we make an outline on the pharmacology research advance of Sophora alkaloids.

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Available abstract

Sophora alkaloids,isolated from Leguminosae Sophora flavescens Ait.,are considered to be the main effective component,which are a class of compounds of matridine-15-ketone basic chemical structure.Sophora alkaloids belong to quinolizidine,which molecular skeleton can be seen as two molecules of quinolizidine fusion.They have ranous pharmacolog fun ction such as regulating blood lipid,anti-arrhythmic,anti-tumor,anti-liver fibrosis,immunity-regulation and so,and they have been applied in clinical widely.In the article we make an outline on the pharmacology research advance of Sophora alkaloids.

Key concepts: Quinolizidine, Sophora, Medicine, Sophora flavescens, Traditional medicine, Alkaloid, Pharmacology, Traditional Chinese medicine

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