The imageological research of low intensity pulsed ultrasound promoting early healing of bone defect in mandible

Objective To explore whether low intensity pulsed ultrasound therapy(LIPUS) can promote the healing of mandibular defect.Method 12 white rabbits(5 months) were assigned to 3 groups randomly.After bone defects were performed in bilateral mandible,all the left side defects received LIPUS for 20 min/day(the treatment group) and the right side received sham LIPUS(the control group) from day 1,until sacrificed on week 1,2,4.After sacrifice,molybdenum target X-ray were performed in turn,and then each radiogram was rated from 0 to 3 followed Nordsletten Scoring Criterion and gray scale was measured and analyzed.Results Gray scale measurements indicated that the healing of mandibular defects in the treatment group were significantly higher than that in the control group(P0.05) after 1 week's and 2 weeks' treatment,however,there were no significant difference between the treatment group and the control group at the end of 4 weeks.Conclution LIPUS can promote the early healing of mandibular defect.