Acute of critical patients complicated by alkalosis an analysis of 769 cases

Objective To study the significance of acute of critical patients complicated by alkalosis and to improve the medical aid.Methods The arterial blood gases, serum electrolytes parameter and clinical data of 769 cases of acute of critical patients were analyzed.Results Acute of critical patients complicated by alkalosis included the following types:216 cases(28.1%)of respiratory accompanied with metabolic alkalosis,159(20.7%)of simple respiratory alkalosis,105(13.6%) of respiratory accompanied with metabolic acidsis,93(12.1%) of simple respiratory,90(11.7%)of triple acid-base disturbance,64(8.3%)of respiratory acidsis accompanied with respiratory and 42( 5.5% ) of metabolic alkalosis accompanied with metabolic acidsis. Among the 769 cases,386 patients(50.2%)PaO 28.0(1 kPa=7.5 mmHg),316 patients(41.1%) died.Conclusions Acute of critical patients complicated by alkalosis is common,with respiratory complicated by metabolic alkalosis and simple respiratory being the most frequently meet.Respiratory caused by primary disease is generally accompanied with hypoxemia.The principle of medical aid is to give active therpy to the primary disease,starting with corredting primary disequilibrium and maintaining electrolyte balance.For patients of severe alkalosis accompanied with multiple organ function injury,hemodialysis or blood ultrafiltration might be applied to correct serious alkalemia and excessive volume overload,so as to restore the pH balance as quickly as possible,which is of great importance.