Curative Effect and Safety of Different Doses of Aminophylline in the Treatment of Asthma in Children

Objective:To investigate the clinical effect of different doses of Aminophylline in the treatment of asthma in children.Method:Selecting 222 children with asthma from May 2008 to May 2012 in our hospital,according to the plan,they were divided into two groups,111 cases in each group,observation group was given oxygen atomizing inhalation of Aminophylline method,and control group was treated with a single intravenous Aminophylline method,the symptoms disappeared time, clinical effect and adverse effect of two groups were compared.Result:In the observation group,shortness of breath disappear time was(0.67±0.29)d,was significantly less than that of control group(0.98±0.21)d.The wheezing disappearance time(1.05±0.31)d was obviously less than that of control group(1.87±0.47)d.The effective rate of the observation group(80.2%) was significantly higher than that of control group(55.9%),the total adverse reaction rate of the observation group(0.9%) was significantly lower than that of control group(12.6%).Conclusion:Fractional oxygen atomizing inhalation of Aminophylline in the treatment of infantile bronchiolitis clinical symptoms disappeares quickly,has good effect and low incidence of adverse reactions,is suitable for wide clinical application.