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The study of relationship between virus myocarditis and tumor necrosis factor

Yan Wang

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Abstract

Objective: To analyze serum levels of tumor necrosis factor (TNF) in patients with acute viral myocarditis (VM) and determine its effects on the pathogenesis of VM. Methods: The serum levels of tumor necrosis factor (TNF α) from 31 patients with virus myocarditis and 32 of healthy people were studied by radioimmunoassay. Result: The result showed that the serum levels of TNF α were remark higher than of normal group, with significant differences in various periods with virus myocarditis, and correlated with the severity of virus myocarditis. Conclusion: It proves that TNF α take part in the occurrence and development of virus myocarditis,the change of concentration of TNF α maybe have double function.

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What this paper is about

Objective: To analyze serum levels of tumor necrosis factor (TNF) in patients with acute viral myocarditis (VM) and determine its effects on the pathogenesis of VM. Methods: The serum levels of tumor necrosis factor (TNF α) from 31 patients with virus myocarditis and 32 of healthy people were studied by radioimmunoassay. Result: The result showed that the serum levels of TNF α were remark higher than of normal group, with significant differences in various periods with virus myocarditis, and correlated with the severity of virus myocarditis. Conclusion: It proves that TNF α take part in the occurrence and development of virus myocarditis,the change of concentration of TNF α maybe have double function.

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Available abstract

Objective: To analyze serum levels of tumor necrosis factor (TNF) in patients with acute viral myocarditis (VM) and determine its effects on the pathogenesis of VM. Methods: The serum levels of tumor necrosis factor (TNF α) from 31 patients with virus myocarditis and 32 of healthy people were studied by radioimmunoassay. Result: The result showed that the serum levels of TNF α were remark higher than of normal group, with significant differences in various periods with virus myocarditis, and correlated with the severity of virus myocarditis. Conclusion: It proves that TNF α take part in the occurrence and development of virus myocarditis,the change of concentration of TNF α maybe have double function.

Key concepts: Viral Myocarditis, Myocarditis, Tumor necrosis factor alpha, Virus, Pathogenesis, Medicine, Tumor necrosis factor α, Radioimmunoassay

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