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2010•Zhongguo xumu zazhiRequires access

Developmental Expression Changes of PPARGC1A Gene in Longissimus Dorsi Muscle of the Tibetan Pigs

LI Xue-wei

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Abstract

The expression changes of peroxisome proliferators activated receptor γ coactivator 1α (PPARGC1A) gene in longissimus dorsi muscle of Tibetan pigs at four postnatal growth stages (2,4,6 and 8 months) were measured by using real-time quantitative PCR approach.The results indicated that the mRNA abundance of PPARGC1A gene was lowest at 2-month,then strongly up-regulated to a higher level at 4-month (P 0.01).After a slight down-regulation during 4-to 6-month (P 0.05),the highest mRNA abundance was observed at 8-month(P 0.01).These results highlight PPARGC1A as a possible candidate genes for pork quality traits and provide some data on which to base further study of the molecular basis of skeletal muscles growth.

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What this paper is about

The expression changes of peroxisome proliferators activated receptor γ coactivator 1α (PPARGC1A) gene in longissimus dorsi muscle of Tibetan pigs at four postnatal growth stages (2,4,6 and 8 months) were measured by using real-time quantitative PCR approach.The results indicated that the mRNA abundance of PPARGC1A gene was lowest at 2-month,then strongly up-regulated to a higher level at 4-month (P 0.01).After a slight down-regulation during 4-to 6-month (P 0.05),the highest mRNA abundance was observed at 8-month(P 0.01).These results highlight PPARGC1A as a possible candidate genes for pork quality traits and provide some data on which to base further study of the molecular basis of skeletal muscles growth.

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Available abstract

The expression changes of peroxisome proliferators activated receptor γ coactivator 1α (PPARGC1A) gene in longissimus dorsi muscle of Tibetan pigs at four postnatal growth stages (2,4,6 and 8 months) were measured by using real-time quantitative PCR approach.The results indicated that the mRNA abundance of PPARGC1A gene was lowest at 2-month,then strongly up-regulated to a higher level at 4-month (P 0.01).After a slight down-regulation during 4-to 6-month (P 0.05),the highest mRNA abundance was observed at 8-month(P 0.01).These results highlight PPARGC1A as a possible candidate genes for pork quality traits and provide some data on which to base further study of the molecular basis of skeletal muscles growth.

Key concepts: PPARGC1A, Longissimus dorsi, Gene expression, Biology, Gene, Messenger RNA, Skeletal muscle, Coactivator

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