A Study on HBsAg Carrier Rate of Children under Age Five in Danzhou City

Objective:To learn the state of HBsAg carrier after implementating vaccine hepatitis B immunization program for children in Danzhou,and providing a scientific basis for the development of the hepatitis B vaccination strategies.Methods:A combination of stratified sampling and mechanical sampling method was carried out,we surveyed vaccine immunization history with hepatitis B in these children who were born from January 1,2008 to December 31,2012,then collected blood 3ML and detected HBsAg carrier status by ELISA from these surveyed children.Results:250children were included in the survey,the 24 hours of birth Hepatitis B vaccine coverage rate in urban,rural newborns was 97.6% and 93.6%,respectively,hepatitis B vaccine three-pin vaccination rate for the whole vaccination course were 100%,only two children from rural HBsAg carrier was positive,and their positive carrier rate was 0.8%,below 1%.Two HBsAg-positive carrier children from rural area and their families were under epidemiological investigation,with discovery that their mothers were carriers of HBsAg,considered as mother to child transmission.Conclusions:Strengthen propaganda prevention to expand knowledge of Hepatitis B and to improve neonatal hepatitis B vaccine 24 hours of the first dose timely rate,and standardize hepatitis B vaccine three-pin Qualified vaccination rate for the whole vaccination course in children.Take effective measures to improve PMTCT rate,it can reduce child carrier rate of hepatitis B surface antigen,and take effective measures to improve PMTCT rates,it will reduce children carrier rate of HBsAg.