2000•Zhongguo bingli shengli zazhiRequires access

Effect of lipopolysaccharide on apoptosis of human umbilical vein endothelial cells

Jianchun Wang

Abstract

AIM: To explore the mechanism of lipopolysaccharide (LPS) on vascular endothelial cell(VEC) damage. METHODS: By using cytometry techniques, we studied the effects of LPS on apoptosis of human umbilical vein endothelial cells (HUVECs) in vitro . RESULTS: LPS was able to induce apoptosis of HUVECs in a time-dose-dependent fashion.CONCLUSION:Apoptosis might play a role in LPS-induced damage of vascular endothelial cells.

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Key concepts: Umbilical vein, Apoptosis, Lipopolysaccharide, Flow cytometry, Endothelial stem cell, In vitro, Human umbilical vein endothelial cell, Cell biology