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The inhibitory effect of compound Liuyuexue on on HBV in vitro

Renbin Huang

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Abstract

Objective To study the inhibitory effect of traditional Chinese medicine compound Liuyuexue on HBV in vitro.Methods At non-cellulotoxic concentration,the different concentrations of CLYX were added respectively to HepG2.2.15 cells, which were incubated subsequently.4 days and 8 days after treatment with drugs,the culture media were collected for determination of the quantity of HBV DNA detected by real time fluorescence quantitative PCR (FQ-PCR) and the levels of HBsAg and HBeAg by ELISA.Results CLYX at the largest non-cellulotoxic concentration could decrease the HBV DNA level and suppress HBsAg and HBeAg expression in HepG2.2.15 cell.Conclusion CLYX can inhibit significantly HBV in vitro.

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What this paper is about

Objective To study the inhibitory effect of traditional Chinese medicine compound Liuyuexue on HBV in vitro.Methods At non-cellulotoxic concentration,the different concentrations of CLYX were added respectively to HepG2.2.15 cells, which were incubated subsequently.4 days and 8 days after treatment with drugs,the culture media were collected for determination of the quantity of HBV DNA detected by real time fluorescence quantitative PCR (FQ-PCR) and the levels of HBsAg and HBeAg by ELISA.Results CLYX at the largest non-cellulotoxic concentration could decrease the HBV DNA level and suppress HBsAg and HBeAg expression in HepG2.2.15 cell.Conclusion CLYX can inhibit significantly HBV in vitro.

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Available abstract

Objective To study the inhibitory effect of traditional Chinese medicine compound Liuyuexue on HBV in vitro.Methods At non-cellulotoxic concentration,the different concentrations of CLYX were added respectively to HepG2.2.15 cells, which were incubated subsequently.4 days and 8 days after treatment with drugs,the culture media were collected for determination of the quantity of HBV DNA detected by real time fluorescence quantitative PCR (FQ-PCR) and the levels of HBsAg and HBeAg by ELISA.Results CLYX at the largest non-cellulotoxic concentration could decrease the HBV DNA level and suppress HBsAg and HBeAg expression in HepG2.2.15 cell.Conclusion CLYX can inhibit significantly HBV in vitro.

Key concepts: HBeAg, HBsAg, In vitro, Medicine, Virology, Real-time polymerase chain reaction, Inhibitory postsynaptic potential, Molecular biology

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