ScholarLens Back to search
2002•Journal of Hengyang Medical CollegeRequires access

Clinical Evaluation of CD_(34) in the Diagnosis of Gastrointestinal Stromal Tumors

Liao Ai-jun

Open publisher page 0 citations

Abstract

Objective:To evaluate the clinical significance of CD 34 in the diagnosis of gastrointestinal stromal tumors (GISTs). Methods:Immunohistochemical assays of CD 34 , vimentin, Desmin, actin, and S-100 were used in 35 cases of GISTs. Results:There were 14 cases benignancy, 9 cases potential malignancy and 12 cases malignancy in the 35 cases of GISTs. Immunohistochemical percentage of positivity was as follows: vimentin 100%(35/35) ,CD 34 85.7%(30/35), actin 23.9%(8/35), Desmin 5.7%(2/35) in 35 cases of GISTs. There was no difference from CD 34 between benign and malignant GISTs (P0.05). Conclusions:CD 34 plays an important role in diagnosis and differential diagnosis of GISTs, but it can′t differentiate between benignancy and malignantancy.

About this research paper

What this paper is about

Objective:To evaluate the clinical significance of CD 34 in the diagnosis of gastrointestinal stromal tumors (GISTs). Methods:Immunohistochemical assays of CD 34 , vimentin, Desmin, actin, and S-100 were used in 35 cases of GISTs. Results:There were 14 cases benignancy, 9 cases potential malignancy and 12 cases malignancy in the 35 cases of GISTs. Immunohistochemical percentage of positivity was as follows: vimentin 100%(35/35) ,CD 34 85.7%(30/35), actin 23.9%(8/35), Desmin 5.7%(2/35) in 35 cases of GISTs. There was no difference from CD 34 between benign and malignant GISTs (P0.05). Conclusions:CD 34 plays an important role in diagnosis and differential diagnosis of GISTs, but it can′t differentiate between benignancy and malignantancy.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective:To evaluate the clinical significance of CD 34 in the diagnosis of gastrointestinal stromal tumors (GISTs). Methods:Immunohistochemical assays of CD 34 , vimentin, Desmin, actin, and S-100 were used in 35 cases of GISTs. Results:There were 14 cases benignancy, 9 cases potential malignancy and 12 cases malignancy in the 35 cases of GISTs. Immunohistochemical percentage of positivity was as follows: vimentin 100%(35/35) ,CD 34 85.7%(30/35), actin 23.9%(8/35), Desmin 5.7%(2/35) in 35 cases of GISTs. There was no difference from CD 34 between benign and malignant GISTs (P0.05). Conclusions:CD 34 plays an important role in diagnosis and differential diagnosis of GISTs, but it can′t differentiate between benignancy and malignantancy.

Key concepts: Desmin, Vimentin, Malignancy, Immunohistochemistry, Medicine, Pathology, Differential diagnosis, Stromal cell

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Clinical Evaluation of CD_(34) in the Diagnosis of Gastrointestinal Stromal Tumors — Research Paper | ScholarLens