2010•Zhongyi-yao xuebaoRequires access

Study on the Percutaneous Absorption of Piperine with Different Penetration-Orange Essential Oil

Yang Zhong-lin

Abstract

Objective:To study the percutaneous absorption of H cataplasm with different penetration enhancers and to determine the best penetration enhancer to prepare the H cataplasm. Methods: Using rabbit skin as transdermal barrier,the penetration percentage of piperine in different cataplasm with different penetration enhancers-Clover Oil and Orange Essential Oil were determined with the Franz diffusing cells. The content of piperine permeated through the rabbit skin was determined by HPLC. Results: The Q of piperine with Clover Oil and Orange Essential Oil were 4. 46 ± 0. 28μg· cm-2,6. 01 ± 0. 37μg·cm-2 respectively. Conclusion: The penetration efficiency of Orange Essential Oil is better than Clover Oil.

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Key concepts: Piperine, Essential oil, Penetration (warfare), Orange (colour), Chemistry, Chromatography, Traditional medicine, Food science