Establishment of automatic biochemical analyzer calibration cycle of biochemical tests

Objective By Hitachi 7180 automatic biochemical analyzer for quality control serum biochemical tests,to determine the calibration cycle in the 16 conventional biochemical tests.Methods After calibration,0h,2h,4h,6h,8h,10h,12h,24h from calibration time three concentration levels were measured on the control serum once,tested once every 24h,totally measured for 30 d to accumulate CV 1 / 6 CLIA'88 permissible error as a criterion to determine the longest calibration cycles of biological and chemical items.Results The calibration cycle in 16 conventional biochemical tests was Cr 2d,Urea 5d,UA 7d,LDH and Tbil Glu 14d,TP 20d,ALB TG 22d,TCHOL HDL 25d,the remaining items HDL,ALT,AST,CK,AMY calibration cycle of 30 d.Conclusion Scientific and rational way to establish the calibration cycle and regular calibration on biochemical analyzer is the basic security measures to ensure the reliability of biochemical test results.