Anti-tuberculosis antibody test and result analysis

Objective Discuss the diagnostic value for tuberculosis with combination of three antibody test methods of LAM-IgG,TB-Dot,ICT.Methods Withdraw serum(pleural fluid,ascites,BALF,cerebrospinal fluid),and test TB antibodies simultaneously using LAM-IgG、TB-Dot、ICT methods.Results Bacillus positive pulmonary tuberculosis for the three methods was 45.3%、63.5% and 69.1% positive respectively,with 3 methods all positive 33.1% and any two of the three positive 23.7%,adding up to 56.8%.Bacillus negative pulmonary tuberculosis for the three methods was 24.6%、39.3% and 39.5% positive respectively,with all three positive 15.4% and any two of them positive 18.4%,adding up to 33.8%,significantly different compared with nontuberculosis group.For bacillus positive and negative pulmonary tuberculosis the three methods all failed to produce in 25.3% and 37.0% of both respectively.Conclusion Antituberculosis antibody test especially using 3 methods simutaneouely is one of the major basis for the tuberculosis diagnosis and differential diagnosis.But in some serious pulmonary tuberculosis patients,patients with complications such as diabetes mellitus and old pulmonary tuberculosis patiente the positive rate is low.In addition,the antibody level in tuberculosis serositis is significantly lower than in pulmonary tuberculosis.