Clinical effect of electronic PCA infusion of propofol mixed remifentanil in total intravenous anesthesia

OBJECTIVE To study the feasibility and superiority of Propofol mixed Remifentanil with electronic PCA pumped infusion versus traditional infusion of Propofol and Fentanyl for total intravenous anesthesia(TIVA).METHODS 76 ASAⅠ-Ⅱ patients scheduled for general anesthesia and PCIA were randomly devided into two groups:group P and T﹙38 patients in each group﹚,they received electronic PCA pumped infusion of propofol mixed Remifentanil and intermitently intravenous infusion of propofol combined fentanyl respectively.The following were recorded carefully and compared between group P and T.The changes in MAP and HR during induction of anesthesia and tracheal intubation;Recovery of spontanous breathing after termination of anesthesia;The duration of leavingaway operating room;the time of eye opening and tracheal extubation after termination of anesthesia;The OAAS,VRS,BCS scores on different time after operation;During the anesthesia the patients of Atropin、Diltiazem and Ephedrine usage,and the times of Atracurium usage;Side effect and complicants such as nausea、vomitting、chill、awake delay or alergic reaction,etc.RESULTS After induction of anesthesia the MAP and HR were lower than that before induction of two groups,and they were lower significantly than the basic level in P group;During intubation,there were slightly changes in the MAP and HR and no intubation response in group P,while in group T there were significant changes in MAP and HR with high incidence of intubation response.The patients of Ephedrine and Diltiazem usage in group T were more than that of group P,but patients of Atropin usage in group T were less than that of group P.During the operation the MAP、HR in group P were stabler than that of group T.The mean times of Atracurium usage in group P were less than that in group T.The duration from termination anesthesia to recovery of spontaneous breathing、eye opening of request、tracheal extubation and leavingaway operating room were significantly shorter in group P than that of group T.After operation the OAAS scores was hihger in group P than that in group T,while the VRS and BCS scores were similar between the two groups by virtue of perfect postoperation controlled analgesia (P0.05).The incidence of side effects and complications was not significantly different between the two groups. CONCLUSION The anesthesia with the electronic PCA infusion of Propofol mixed Remifentanil remains stable in TIVA,and being regulated easily.It is named subTCI.