Analysis of the Pathogen Distribution and Drug Sensitivity of Diabetic Patients with Urinary Tract Infection

Objective To investigate the pathogen distribution and antimicrobial resistance in diabetes complicated by urinary tract infection so as to provide guidance for clinical rational use of antibiotics. Methods A retrospective analysis was conducted on 69 cases with diabetes and urinary tract infection hospitalized in our hospital from June 2011 to June 2014. Results A total of 92 strains of pathogenic bacteria were detected from the midstream specimens of urine of 69 cases with diabetes and urinary tract infection, of which, there were 60 strains of gram-negative bacilli, accounting for 65.21%; 25 strains of gram-positive bacteria, accounting for 27.17%; 7 strains of fungi, accounting for 7.61%. Gram-negative bacilli were highly sensitive to imipenem. Gram-positive bacteria had low rate of drug resistance to piperacillin/tazobactam and vancomycin, but had high rate of drug resistance to other antibacterial drugs, which reached 40%~77%. Staphylococcus aureus was highly sensitive to vancomycin, its rate of drug resistance to penicillin reached 90%, to erythromycin reached 85.5%. Conclusion The pathogens of diabetes complicated by urinary tract infection are mainly gram-negative bacilli, followed by gram-positive cocci and fungi, and they have high rate of resistance to common antimicrobials and prevalence of multidrug resistance generally. Thus, carrying out the monitoring of pathogens and drug resistance is of positive significance in improving the level of diagnosis and treatment of diabetes complicated by urinary tract infection.