Application of exhaled nitric oxide monitoring combined with allergen skin prick test in children with asthma

Objective To study the application value of exhaled nitric oxide monitoring combined with allergen skin prick test in children with asthma.Methods 72 children with asthma were taken as the test group and another 72 healthy children as the normal group.Exhaled nitric oxide in children with asthma and allergen skin prick test results were compared between the two groups before and after the treatment.Results Before the treatment,the concentration of exhaled nitric oxide was significantly higher in the test group than in the normal group,and it decreased obviously in the test group after the treatment.There existed a certain degree of allergic response to12 kinds of allergens,which the dust mite showed the highest positive rate.Conclusion Monitoring of exhaled nitric oxide and allergen skin prick test can effectively indicate the development of childhood asthma,which play a key role in the treatment therapy.