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The Influence of Needling Baihui and Dazhui on GSH-PX and CAT in A Rat Model of Vascular Dementia

Zhu Chongxia

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Abstract

Purpose To investigate the influence of needling Baihui and Dazhui on learning, memory, glutathion peroxidase (GSH PX) and catalase (CAT) in a rat model of vascular dementia (VD). Methods Thirty six Wester rats were randomly divided into sham operation, model, acupuncture and Western medicine groups, 9 rats each group. A rat VD model was made by vessel occlusion and treated for 30 days. Rat's learning ability and memory were tested with a rat running box and intracerebral activity of GSH PX and CAT was determined. Results Needling points Baihui and Dazhui markedly decreased the number and time of electric shock to a VD rat in a running box experiment and increased the activity of GSH PX and CAT. Conclusion Needling points Baihui and Dazhui can improve learning ability and memory, and free radical metabolism in VD rats.

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Purpose To investigate the influence of needling Baihui and Dazhui on learning, memory, glutathion peroxidase (GSH PX) and catalase (CAT) in a rat model of vascular dementia (VD). Methods Thirty six Wester rats were randomly divided into sham operation, model, acupuncture and Western medicine groups, 9 rats each group. A rat VD model was made by vessel occlusion and treated for 30 days. Rat's learning ability and memory were tested with a rat running box and intracerebral activity of GSH PX and CAT was determined. Results Needling points Baihui and Dazhui markedly decreased the number and time of electric shock to a VD rat in a running box experiment and increased the activity of GSH PX and CAT. Conclusion Needling points Baihui and Dazhui can improve learning ability and memory, and free radical metabolism in VD rats.

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Available abstract

Purpose To investigate the influence of needling Baihui and Dazhui on learning, memory, glutathion peroxidase (GSH PX) and catalase (CAT) in a rat model of vascular dementia (VD). Methods Thirty six Wester rats were randomly divided into sham operation, model, acupuncture and Western medicine groups, 9 rats each group. A rat VD model was made by vessel occlusion and treated for 30 days. Rat's learning ability and memory were tested with a rat running box and intracerebral activity of GSH PX and CAT was determined. Results Needling points Baihui and Dazhui markedly decreased the number and time of electric shock to a VD rat in a running box experiment and increased the activity of GSH PX and CAT. Conclusion Needling points Baihui and Dazhui can improve learning ability and memory, and free radical metabolism in VD rats.

Key concepts: Dry needling, Vascular dementia, Acupuncture, Glutathione peroxidase, Medicine, Rat model, Occlusion, Catalase

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