Clinical diagnosis of pancreas cystic lesions

Objective To investigate the clinical features and diagnostic methods of pancreas cystic lesions. Methods The clinical characteristics of 125 cases of pancreas cystic lesions patients were analyzed, including age, gender, course of disease, medical history, complications, symptoms, signs and radiological data, endoscopic ultrasound(EUS) and endoscopic ultrasound guided fine needle aspiration(EUS-FNA), surgical pathology. Results There were 92 cases of pancreas pseudocyst, 2 cases of true pancreas cyst, 8 cases of pancreas cystic neoplasms, and 23 cases of unknown character of space-occupying cystic lesions of the pancreas. There were more female in cystic neoplasms and true pancreas cyst patients than those in pseudocyst patients; Compared to the true cyst group and the cystic neoplasms group; more patients among the pseudocyst group reported the history of acute or chronic pancreatitis; biliary calculi was more frequently discovered among the pseudocyst group than that in the cystic neoplasms group. Clinical characteristics of each group had no significant difference. EUS and EUS-FNA can improve diagnostic accuracy. Conclusions Pancreatic cystic disease is not uncommon. Pancreas pseudocyst are the major pancreatic cyst and more with pancreatitis and biliary disease. Comprehensive analysis is necessary by combining a variety of imaging, EUS, EUS-FNA and pathology, because clinical characteristics of pancreas cystic lesions have no significant difference. The role of EUS and EUS-FNA for differentiating benign and malignant cystic lesions have become increasingly prominent.