2008International Journal of Digestive DiseasesRequires access

Progress in specific-targeting hepatic stellate cell of liver fibrosis therapy

LI Dinggu

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Abstract

Liver fibrosis is a chronic liver disease development process to go through a histological change.Hepatic stellate cell(HSC) is the central link in the activation and proliferation of liver fibrosis.Recent studies indicate that regulating gene therapy and receptor-mediated medicine can be used in targeting HSC,which will further improve liver specificity and develop new approach to clinical application.

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What this paper is about

Liver fibrosis is a chronic liver disease development process to go through a histological change.Hepatic stellate cell(HSC) is the central link in the activation and proliferation of liver fibrosis.Recent studies indicate that regulating gene therapy and receptor-mediated medicine can be used in targeting HSC,which will further improve liver specificity and develop new approach to clinical application.

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Available abstract

Liver fibrosis is a chronic liver disease development process to go through a histological change.Hepatic stellate cell(HSC) is the central link in the activation and proliferation of liver fibrosis.Recent studies indicate that regulating gene therapy and receptor-mediated medicine can be used in targeting HSC,which will further improve liver specificity and develop new approach to clinical application.

Key concepts: Hepatic stellate cell, Liver fibrosis, Hepatic fibrosis, Medicine, Fibrosis, Genetic enhancement, Chronic liver disease, Liver disease

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